Bio-Santee Chem 

 A unique balanced combination of Calcium and Vitamin D allow  AIRBORNE to make the patients life better. Our unbeatable technology also help to get more absorption  in the body.

Calcium, the most abundant mineral in the body, is found in some foods, added to others, available as a dietary supplement, and present in some medicines (such as antacids). Calcium is required for muscle contraction, blood vessel expansion and contraction, secretion of hormones and enzymes, and transmitting impulses throughout the nervous system [1]. The body strives to maintain constant concentrations of calcium in blood, muscle, and intercellular fluids, though less than <1% of total body calcium is needed to support these functions.

The remaining 99% of the body's calcium supply is stored in the bones and teeth where it supports their structure [2]. Bone itself undergoes continuous remodeling, with constant resorption and deposition of calcium into new bone [1]. The balance between bone resorption and deposition changes with age. Bone formation exceeds resorption in growing children, whereas in early and middle adulthood both processes are relatively equal. In aging adults, particularly among postmenopausal women, bone breakdown exceeds formation, resulting in bone loss that increases the risk of osteoporosis over time [1].

Recommended Intakes

Intake recommendations for calcium and other nutrients are provided in the Dietary Reference Intakes

(DRIs) developed by the Food and Nutrition Board (FNB) at the Institute of Medicine of the National Academies (formerly National Academy of Sciences) [1]. DRI is the general term for a set of reference values used for planning and assessing the nutrient intakes of healthy people. These values, which vary by age and gender [1], include:

• Recommended Dietary Allowance (RDA): average daily level of intake sufficient to meet the nutrient requirements of nearly all (97%-98%) healthy individuals.
• Adequate Intake (AI): established when evidence is insufficient to develop an RDA and is set at a level assumed to ensure nutritional adequacy.
• Tolerable Upper Intake Level (UL): maximum daily intake unlikely to cause adverse health effects [1].

The FNB established AIs for the amounts of calcium required to maintain adequate rates of calcium retention and bone health in healthy people. They are listed in Table 1 in milligrams (mg) per day.

Table 1: Adequate Intakes (AIs) for Calcium [1]

mg = milligrams

Signs of Calcium Deficiency:

• Aching joints
• Associated with cognitive impairment, convulsions, depression, delusions and hyperactivity
• Brittle nails
• Eczema
• Elevated blood cholesterol
• Heart palpitations
• Hypertension (high blood pressure)
• Insomnia
• Muscle cramps
• Nervousness
• Numbness in the arms and/or legs
• Pasty complexion
• Rheumatoid arthritis
• Rickets
• Tooth decay

Health concerns – Calcium is used for:

• Celiac disease
• Gingivitis (periodontal disease)
• Kidney stones / Psorasis
• Cancer prevention (Colorectal, Breast, Prostate)
• Multiple sclerosis
• Painful menstruation (dysmenorrhea)
• Pregnancy and postpartum support
• Premenstrual syndrome
• Rickets / Oesteoprosis

What Calcium Does:

• Aids in neuromuscular activity
• Essential in blood clotting
• Formation of strong bones and teeth and maintenance of healthy gums
• Healthy skin
• Helps prevent cancer
• Helps prevent cardiovascular disease
• Involved in the activation of several enzymes, including lipase (which breaks down fat for utilization by the body)
• Lowers cholesterol levels
• Maintains proper cell membrane permeability
• Maintenance of a regular heartbeat
• May increase the rate of bone growth and bone mineral density in children
• May lower blood pressure
• Needed for muscular growth and contraction
• Participates in the protein structuring of RNA and DNA
• Prevent bone loss associated with osteoporosis
• Prevention of muscle cramps
• Protects against the development of preclampsia during pregnancy
• Protects bones and teeth from lead by inhibiting absorption of this toxic metal
• Provides energy
• Transmission of nerve impulses

 Cautions & Comments for Calcium

• A diet high in protein, fat and/or sugar affects calcium uptake
• Amino acid lysine is needed for calcium absorption.  Food sources of lysine include cheese, eggs, fish, lima beans, milk potatoes, red meat, soy products, and yeast or supplement form
• Antacids such as Tums are not recommended as a source of calcium because they neutralize the stomach acid needed for calcium absorption
• Calcium may interfere with the effects of verapamil (Calan, Isoptin, Verelan)
• A calcium channel blocker sometimes prescribed for heart problems and high blood pressure. 
• Calcium supplements are more effective when taken in smaller doses spread throughout the day and before bedtime
• Calcium supplements should not be taken by persons with a history of kidney stones or kidney disease
• Consuming alcoholic beverages, coffee, junk foods, excess salt, and/or white flour also leads to the loss of calcium by the body
• Female athletes and menopausal women need greater amounts of calcium than other women because their estrogen levels are lower
• Heavy exercising hinders calcium uptake, but moderate exercise promotes it.

Before Using

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Problems in children have not been reported with intake of normal daily recommended amounts. Injectable forms of calcium should not be given to children because of the risk of irritating the injection site.

Geriatric

Problems in older adults have not been reported with intake of normal daily recommended amounts. It is important that older people continue to receive enough calcium in their daily diets. However, some older people may need to take extra calcium or larger doses because they do not absorb calcium as well as younger people. Check with your health care professional if you have any questions about the amount of calcium you should be taking in each day.

Pregnancy

It is especially important that you are receiving enough calcium when you become pregnant and that you continue to receive the right amount of calcium throughout your pregnancy. The healthy growth and development of the fetus depend on a steady supply of nutrients from the mother. However, taking large amounts of a dietary supplement during pregnancy may be harmful to the mother and/or fetus and should be avoided.

Breastfeeding

It is especially important that you receive the right amount of calcium so that your baby will also get the calcium needed to grow properly. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Drug Interactions

Using dietary supplements in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Altretamine
• Amygdalin
• Digoxin
• Eltrombopag
• Levomethadyl
• Licorice
• Mycophenolate Mofetil
• Mycophenolic Acid

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of dietary supplements in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Diarrhea or
• Stomach or intestinal problems—Extra calcium or specific calcium preparations may be necessary in these conditions.
• Heart disease—Calcium by injection may increase the chance of irregular heartbeat.
• Hypercalcemia (too much calcium in the blood) or
• Hypercalciuria (too much calcium in the urine)—Calcium supplements may make these conditions worse.
• Hyperparathyroidism or
• Sarcoidosis—Calcium supplements may increase the chance of hypercalcemia (too much calcium in the blood).
• Hypoparathyroidism—Use of calcium phosphate may cause high blood levels of phosphorus which could increase the chance of side effects.
• Kidney disease or stones—Too much calcium may increase the chance of kidney stones.

Proper Use

Drink a full glass (8 ounces) of water or juice when taking a calcium supplement. However, if you are taking calcium carbonate as a phosphate binder in kidney dialysis, it is not necessary to drink a glass of water.

This dietary supplement is best taken 1 to 1½ hours after meals, unless otherwise directed by your health care professional. However, patients with a condition known as achlorhydria may not absorb calcium supplements on an empty stomach and should take them with meals.

For individuals taking the chewable tablet form of this dietary supplement:

• Chew the tablets completely before swallowing.

For individuals taking the syrup form of this dietary supplement:

• Take the syrup before meals. This will allow the dietary supplement to work faster.
• Mix in water or fruit juice for infants or children.

Take this dietary supplement only as directed. Do not take more of it and do not take it more often than recommended on the label. To do so may increase the chance of side effects.

Dosing

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (capsules, chewable tablets, lozenges, oral solution, oral suspension, syrup, tablets, extended-release tablets, tablets for solution):
• To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes (Note that the normal daily recommended intakes are expressed as an actual amount of calcium. The salt form [e.g., calcium carbonate, calcium gluconate, etc.] has a different strength):

For the U.S.

• Adults and teenagers—800 to 1200 milligrams (mg) per day.
• Pregnant and breast-feeding females—1200 mg per day.
• Children 4 to 10 years of age—800 mg per day.
• Children birth to 3 years of age—400 to 800 mg per day.

For Canada

• Adults and teenagers—800 to 1100 mg per day.
• Adult and teenage females—700 to 1100 mg per day.
• Pregnant and breast-feeding females—1200 to 1500 mg per day.
• Children 7 to 10 years of age—700 to 1100 mg per day.
• Children 4 to 6 years of age—600 mg per day.
• Children birth to 3 years of age—250 to 550 mg per day.

• To treat deficiency:
• Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions

If this dietary supplement has been ordered for you by your health care professional and you will be taking it in large doses or for a long time, your health care professional should check your progress at regular visits. This is to make sure the calcium is working properly and does not cause unwanted effects.

Do not take calcium supplements within 1 to 2 hours of taking other medicine by mouth. To do so may keep the other medicine from working properly.

Unless you are otherwise directed by your health care professional, to make sure that calcium is used properly by your body:

• Do not take other medicines or dietary supplements containing large amounts of calcium, phosphates, magnesium, or vitamin D unless your health care professional has told you to do so or approved.
• Do not take calcium supplements within 1 to 2 hours of eating large amounts of fiber-containing foods, such as bran and whole-grain cereals or breads, especially if you are being treated for hypocalcemia (not enough calcium in your blood).
• Do not drink large amounts of alcohol or caffeine-containing beverages (usually more than 8 cups of coffee a day), or use tobacco.

Some calcium carbonate tablets have been shown to break up too slowly in the stomach to be properly absorbed into the body. If the calcium carbonate tablets you purchase are not specifically labeled as being "USP," check with your pharmacist. He or she may be able to help you determine which tablets are best.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Although the following side effects occur very rarely when the calcium supplement is taken as recommended, they may be more likely to occur if it is taken in large doses, if it is taken for a long time or if it is taken by patients with kidney disease.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Dizziness
• Flushing and/or sensation of warmth or heat
• Irregular heartbeat
• Nausea or vomiting
• Skin redness, rash, pain, or burning at injection site
• Sweating
• Tingling sensation

Rare

• Difficult or painful urination
• Drowsiness
• Nausea or vomiting (continuing)

Early signs of overdose

• Constipation (severe)
• Dryness of mouth
• Headache (continuing)
• Increased thirst
• Irritability
• Loss of appetite
• Mental depression
• Metallic taste
• Unusual tiredness or weakness

Late signs of overdose

• Confusion
• Drowsiness (severe)
• High blood pressure
• Increased sensitivity of eyes or skin to light
• Irregular, fast, or slow heartbeat
• Unusually large amount of urine or increased frequency of urination

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

The U.S. Department of Agriculture’s Nutrient Database Web site, http://www.nal.usda.gov/fnic/foodcomp/search, lists the nutrient content of many foods. It also provides a comprehensive list of foods containing calcium at http://www.nal.usda.gov/fnic/foodcomp/Data/SR20/nutrlist/sr20a301.pdf.

** Calcium content varies slightly by fat content; the more fat, the less calcium the food contains.

*** Calcium content is for tofu processed with a calcium salt. Tofu processed with other salts does not provide significant amounts of calcium.

In its food guidance system, MyPyramid, the U.S. Department of Agriculture recommends that persons aged 9 years and older eat 3 cups of foods from the milk group per day [7]. A cup is equal to 1 cup (8 ounces) of milk, 1 cup of yogurt, 1.5 ounces of natural cheese (such as Cheddar), or 2 ounces of processed cheese (such as American).

Vitamin D

 Vitamin D helps prevent calcium loss from your bones. It is sometimes called "the sunshine vitamin" because it is made in your skin when you are exposed to sunlight. If you get outside in the sunlight every day for 15 to 30 minutes, you should get all the vitamin D you need. However, in northern locations in winter, the sunlight may be too weak to make vitamin D in the skin. Vitamin D may also be obtained from your diet or from multivitamin preparations. Most milk is fortified with vitamin D. The major biologic function of vitamin D is to maintain normal blood levels of calcium and phosphorus. Vitamin D aids in the absorption of calcium, helping to form and maintain strong bones. Recently, research also suggests vitamin D may provide protection from osteoporosis, hypertension (high blood pressure), cancer, and several autoimmune diseases.

Rickets and osteomalacia are classic vitamin D deficiency diseases. In children, vitamin D deficiency causes rickets, which results in skeletal deformities. In adults, vitamin D deficiency can lead to osteomalacia, which results in muscular weakness in addition to weak bones. Populations who may be at a high risk for vitamin D deficiencies include the elderly, obese individuals, exclusively breastfed infants, and those who have limited sun exposure. Also, individuals who have fat malabsorption syndromes (e.g., cystic fibrosis) or inflammatory bowel disease (e.g., Crohn's disease) are at risk.

Dietary supplements
The two main forms of calcium in supplements are carbonate and citrate. Calcium carbonate is more commonly available and is both inexpensive and convenient. Other calcium forms in supplements or fortified foods include gluconate, lactate, and phosphate. Calcium citrate malate is a well-absorbed form of calcium found in some fortified juices [8]. The body absorbs calcium carbonate most efficiently when the supplement is consumed with food, whereas the body can absorb calcium citrate equally effectively when the supplement is taken with or without food [9]

Calcium supplements contain varying amounts of elemental calcium. For example, calcium carbonate is 40% calcium by weight, whereas calcium citrate is 21% calcium.

The percentage of calcium absorbed depends on the total amount of elemental calcium consumed at one time; as the amount increases, the percentage absorption decreases. Absorption is highest in doses ≤500 mg. So, for example, one who takes 1,000 mg/day of calcium from supplements might split the dose and take 500 mg at two separate times during the day.
Some individuals who take calcium supplements might experience gas, bloating, constipation, or a combination of these symptoms. Such symptoms can often be resolved by spreading out the calcium dose throughout the day, taking the supplement with meals.
Medicines
Because of its ability to neutralize stomach acid, calcium carbonate is found in some over-the-counter antacid products, such as Tums® and Rolaids®. Depending on its strength, each chewable pill or soft chew provides 200 to 400 mg of calcium. As noted above, calcium carbonate is an acceptable form of supplemental calcium, especially for individuals who have normal levels of stomach acid.

According to the 2005 Dietary Guidelines for Americans, "nutrient needs should be met primarily through consuming foods. Foods provide an array of nutrients and other compounds that may have beneficial effects on health. In certain cases, fortified foods and dietary supplements may be useful sources of one or more nutrients that otherwise might be consumed in less than recommended amounts. However, dietary supplements, while recommended in some cases, cannot replace a healthful diet.

The Dietary Guidelines for Americans describe a healthy diet as one that:

• Emphasizes a variety of fruits, vegetables, whole grains, and fat-free or low-fat milk and milk products:

Many dairy products, such as milk, cheese, and yogurt, are rich sources of calcium. Some vegetables provide significant amounts of calcium, as do some fortified cereals and juices.

• Includes lean meats, poultry, fish, beans, eggs, and nuts.
• Tofu made with calcium salts is a good source of calcium, as are canned sardines and salmon with soft bones.
• Is low in saturated fats, trans fats, cholesterol, salt (sodium), and added sugars.

Low- and nonfat dairy products provide amounts of calcium that are roughly similar to the amounts in their full-fat versions.

• Stays within your daily calorie needs.

For more information about building a healthful diet, refer to the Dietary Guidelines for Americans (http://www.health.gov/dietaryguidelines/dga2005/document/default.htm) and the U.S. Department of Agriculture's food guidance system, MyPyramid.

New ultra modified

                ADVANCE TECHNOLGY OF Airborne helps for………….

• Osteoprosis / Loss of Bone Mass
• Pregnancy (Pre & Post Conditions)
• Dysmenorrhea / Menopause
• Muscular / Joint Pains
• Arthritis / Rickets
• Autoimmune Diseases
• Psorasis or Skin Diseases
• Cancers (colorectal, breast, also for Prevention)
• Hypertension

Company Marketing Manager Mr. Nazir Assadi(center) with his Marketing Team including Mr. Mohammad Danish (on right) and Mr. M. Adeel Siddiqui (on left) on Airborne Tablet launching day

Airborne Launching in Asia 2010

Marketing Team Airborne

Bio-Santee Chem has  launched the Airborne in March, 2010 at different parts of the asia including Pakistan, Afghanistan and other countries.

References

1. Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. Washington, DC: National Academy Press, 1997.
2. Weaver CM, Heaney RP. Calcium. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ. Modern Nutrition in Health and Disease. 10th ed. Baltimore, MD: Lippincott Williams & Wilkins, 2006:194-210.
3. Subar AF, Krebs-Smith SM, Cook A, Kahle LL. Dietary sources of nutrients among US adults. J Am Diet Assoc 1998;98:537-47. [PubMed abstract]
4. U.S. Department of Agriculture. USDA Nutrient Database for Standard Reference, Release 16. 2003. http://www.nal.usda.gov/fnic/foodcomp.
5. Pennington J, Bowes A, Church H. Bowes & Church's Food Values of Portions Commonly Used. 17th ed. Philadelphia, PA: Lippincott Williams & Wilkins Publishers, 1998.
6. Heaney RP, Dowell MS, Rafferty K, Bierman J. Bioavailability of the calcium in fortified soy imitation milk, with some observations on method. Am J Clin Nutr 2000;71:1166-9. [PubMed abstract]
7. U.S. Department of Agriculture, Center for Nutrition Policy and Promotion. MyPyramid, 2005. http://www.mypyramid.gov/.
8. Andon MB, Peacock M, Kanerva RL, De Castro JAS. Calcium absorption from apple and orange juice fortified with calcium citrate malate (CCM). J Am Coll Nutr 1996;15:313-6. [PubMed abstract]
9. Straub DA. Calcium supplementation in clinical practice: a review of forms, doses, and indications. Nutr Clin Pract. 2007;22:286-96. [PubMed abstract]
10. U.S. Department of Agriculture. Results from the United States Department of Agriculture's 1994-96 Continuing Survey of Food Intakes by Individuals/Diet and Health Knowledge Survey, 1994-96.
11. Ervin RB, Wang C-Y, Wright JD, Kennedy-Stephenson J. Dietary intake of selected minerals for the United States population: 1999-2000. Advance Data from Vital and Health Statistics, number 341. Hyattsville, MD: National Center for Health Statistics, 2004.
12. National Institutes of Health. Optimal calcium intake. NIH Consensus Statement: 1994;12:1-31. [PubMed abstract]
13. Heaney RP, Recker RR, Stegman MR, Moy AJ. Calcium absorption in women: relationships to calcium intake, estrogen status, and age. J Bone Miner Res 1989;4:469-75. [PubMed abstract]
14. Weaver CM, Heaney RP. Isotopic exchange of ingested calcium between labeled sources: evidence that ingested calcium does not form a common absorptive pool. Calcif Tissue Int 1991;49:244-7. [PubMed abstract]
15. Weaver CM, Heaney RP, Martin BR, Fitzsimmons ML. Human calcium absorption from whole-wheat products. J Nutr 1991;121:1769-75. [PubMed abstract]
16. Weaver CM, Proulx WR, Heaney RP. Choices for achieving adequate dietary calcium with a vegetarian diet. Am J Clin Nutr 1999;70:543S-8S. [PubMed abstract]
17. Heaney RP. Bone mass, nutrition, and other lifestyle factors. Nutr Rev 1996;54:S3-S10. [PubMed abstract]
18. Sellmeyer DE, Schloetter M, Sebastian A. Potassium citrate prevents increased urine calcium excretion and bone resorption induced by a high sodium chloride diet. J Clin Endocrinol Metab 2002;87:2008-12. [PubMed abstract]
19. Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC: National Academies Press, 2004.
20. Barrett-Connor E, Chang JC, Edelstein SL. Coffee-associated osteoporosis offset by daily milk consumption. JAMA 1994;271:280-3. [PubMed abstract]
21. Massey LK, Whiting SJ. Caffeine, urinary calcium, calcium metabolism, and bone. J Nutr 1993;123:1611-4. [PubMed abstract]
22. Hirsch PE, Peng TC. Effects of alcohol on calcium homeostasis and bone. In: Anderson J, Garner S, eds. Calcium and Phosphorus in Health and Disease. Boca Raton, FL: CRC Press, 1996:289-300.
23. Calvo MS. Dietary phosphorus, calcium metabolism and bone. J Nutr 1993;123:1627-33. [PubMed abstract]
24. Heaney RP, Rafferty K. Carbonated beverages and urinary calcium excretion. Am J Clin Nutr 2001;74:343-7. [PubMed abstract]
25. Dawson-Hughes B, Harris SS, Palermo NJ, Castaneda-Sceppa C, Rasmussen HM, Dallal GE. Treatment with potassium bicarbonate lowers calcium excretion and bone resorption in older men and women. J Clin End & Metab 2009;94:96-102. [PubMed abstract]
26. Gallagher JC, Goldgar D, Moy A. Total bone calcium in normal women: effect of age and menopause status. J Bone Min Res 1987;2:491-6. [PubMed abstract]
27. Breslau NA. Calcium, estrogen, and progestin in the treatment of osteoporosis. Rheum Dis Clin North Am 1994;20:691-716. [PubMed abstract]
28. Gallagher JC, Riggs BL, Deluca HF. Effect of estrogen on calcium absorption and serum vitamin D metabolites in postmenopausal osteoporosis. J Clin Endocrinol Metab 1980;51:1359-64. [PubMed abstract]
29. Daniels CE. Estrogen therapy for osteoporosis prevention in postmenopausal women. Pharmacy Update-NIH 2001;March/April.
30. Dawson-Hughes B, Dallal GE, Krall EA, Sadowski L, Sahyoun N, Tannenbaum S. A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. N Engl J Med 1990;323:878-83. [PubMed abstract]
31. Elders PJ, Lips P, Netelenbos JC, van Ginkel FC, Khoe E, van der Vijgh WJ, et al. Long-term effect of calcium supplementation on bone loss in perimenopausal women. J Bone Min Res 1994;9:963-70. [PubMed abstract]
32. Kirschstein R. Menopausal hormone therapy: summary of a scientific workshop. Ann Intern Med 2003;138:361-4. [PubMed abstract]
33. American College of Obstetricians and Gynecologists. Frequently Asked Questions About Hormone Therapy, October 2004. http://www.acog.org/from_home/publications/press_releases/nr10-01-04.cfm.
34. North American Menopause Society. Role of progestogen in hormone therapy for postmenopausal women: position statement of the North American Menopause Society. Menopause 2003;10:113-32. [PubMed abstract]
35. Abrams SA, Silber TJ, Esteban NV, Vieira NE, Stuff JE, Meyers R, et al. Mineral balance and bone turnover in adolescents with anorexia nervosa. J Pediatr 1993;123:326-31. [PubMed abstract]
36. Drinkwater B, Bruemner B, Chesnut C. Menstrual history as a determinant of current bone density in young athletes. JAMA 1990;263:545-8. [PubMed abstract]
37. Marcus R, Cann C, Madvig P, Minkoff J, Goddard M, Bayer M, et al. Menstrual function and bone mass in elite women distance runners: endocrine and metabolic features. Ann Intern Med 1985;102:158-63. [PubMed abstract]
38. Nattiv A. Stress fractures and bone health in track and field athletes. J Sci Med Sport 2000;3:268-79. [PubMed abstract]
39. Johnson AO, Semenya JG, Buchowski MS, Enwonwu CO, Scrimshaw NS. Correlation of lactose maldigestion, lactose intolerance, and milk intolerance. Am J Clin Nutr 1993;57:399-401. [PubMed abstract]
40. Coffin B, Azpiroz F, Guarner F, Mlagelada JR. Selective gastric hypersensitivity and reflex hyporeactivity in functional dyspepsia. Gastroenterology 1994;107:1345-51. [PubMed abstract]
41. Hertzler SR, Huynh B, Savaiano DA. How much lactose is "low lactose." J Am Diet Assoc 1996;96:243-6. [PubMed abstract]
42. Hertzler SR, Savaiano DA. Colonic adaptation to daily lactose feeding in lactose maldigesters reduces lactose intolerance. Am J Clin Nutr 1996;64:232-6. [PubMed abstract]
43. Hertzler SR, Savaiano DA, Levitt MD. Fecal hydrogen production and consumption measurements: response to daily lactose ingestion by lactose maldigesters. Dig Dis Sci 1997;42:348-53. [PubMed abstract]
44. Martini MC, Savaiano DA. Reduced intolerance symptoms from lactose consumed during a meal. Am J Clin Nutr 1988;47:57-60. [PubMed abstract]
45. Nose O, Iida Y, Kai H, Harada T, Ogawa M, Yabuuchi H. Breath hydrogen test for detecting lactose malabsorption in infants and children: prevalence of lactose malabsorption in Japanese children and adults. Arch Dis Child 1979;54:436-40. [PubMed abstract]
46. Rao DR, Bello H, Warren AP, Brown GE. Prevalence of lactose maldigestion: influence and interaction of age, race, and sex. Dig Dis Sci 1994;39:1519-24. [PubMed abstract]
47. Horowitz M, Wishart J, Mundy L, Nordin BEC. Lactose and calcium absorption in postmenopausal osteoporosis. Arch Intern Med 1987;147:534-6. [PubMed abstract]
48. Tremaine WJ, Newcomer AD, Riggs BL, McGill DB. Calcium absorption from milk in lactase-deficient and lactase-sufficient adults. Dig Dis Sci 1986;31:376-8. [PubMed abstract]
49. Suarez FL, Savaiano DA, Arbisi P, Levitt MD. Tolerance to the daily ingestion of two cups of milk by individuals claiming lactose intolerance. Am J Clin Nutr 1997;65:1502-6. [PubMed abstract]
50. Suarez FL, Savaiano DA, Levitt MD. A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance. N Engl J Med 1995;333:1-4. [PubMed abstract]
51. Johnson AO, Semenya JG, Buchowski MS, Enwonwu CO, Scrimshaw NS. Adaptation of lactose maldigester to continued milk intakes. Am J Clin Nutr 1993;58:879-81. [PubMed abstract]
52. Pribila BA, Hertzler SR, Martin BR, Weaver CM, Savaiano DA. Improved lactose digestion and intolerance among African-American adolescent girls fed a dairy-rich diet. J Am Diet Assoc 2000;100:524-8. [PubMed abstract]
53. Marsh AG, Sanchez TV, Midkelsen O, Keiser J, Mayor G. Cortical bone density of adult lacto-ovo-vegetarian and omnivorous women. J Am Diet Assoc 1980;76:148-51. [PubMed abstract]
54. Reed JA, Anderson JJ, Tylavsky FA, Gallagher JCJ. Comparative changes in radial-bone density of elderly female lactoovovegetarians and omnivores. Am J Clin Nutr 1994;59:1197S-202S. [PubMed abstract]
55. Janelle KC, Barr SI. Nutrient intakes and eating behavior scores of vegetarian and nonvegetarian women. J Am Diet Assoc 1995;95:180-6. [PubMed abstract]
56. American Dietetic Association, Dietitians of Canada. Position of the American Dietetic Association and Dietitians of Canada: vegetarian diets. J Am Diet Assoc 2003;103:748-65. [PubMed abstract]
57. National Institutes of Health. Osteoporosis prevention, diagnosis, and therapy. NIH Consensus Statement Online 2000:1-45. [PubMed abstract]
58. Riggs BL, Melton L. The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone 1995;17:505S-11S. [PubMed abstract]
59. National Osteoporosis Foundation. NOF osteoporosis prevention: risk factors for osteoporosis, 2003. http://www.nof.org/prevention/risk.htm.
60. National Osteoporosis Foundation. Bone mineral density testing: what the numbers mean. Bone Health Updates, 2001. http://www.nof.org/osteoporosis/bmdtest.htm.
61. U.S. Food and Drug Administration. Food labeling: health claims; calcium and osteoporosis, and calcium, vitamin D, and osteoporosis. http://www.fda.gov/Food/LabelingNutrition/LabelClaims/HealthClaimsMeetingSignificantScientificAgreementSSA/default.htm.
62. Allender PS, Cutler JA, Follmann D, Cappuccio FP, Pryer J, Elliott P. Dietary calcium and blood pressure. Ann Intern Med 1996;124:825-31. [PubMed abstract]
63. Bucher HC, Cook RJ, Guyatt GH, Lang JD, Cook DJ, Hatala R, et al. Effects of dietary calcium supplementation on blood pressure. JAMA 1996;275:1016-22. [PubMed abstract]
64. McCarron D, Reusser M. Finding consensus in the dietary calcium-blood pressure debate. J Am Coll Nutr 1999;18:398S-405S. [PubMed abstract]
65. Dickinson HO, Nicolson DJ, Cook JV, Campbell F, Beyer FR, Ford GA, et al. Calcium supplementation for the management of primary hypertension in adults. Cochrane Database Syst Rev 2006;(2):CD004639. [PubMed abstract]
66. Rouse IL, Beilin LJ, Armstrong BK, Vandongen R. Blood-pressure-lowering effect of a vegetarian diet: controlled trial in normotensive subjects. Lancet 1983;1:5-10. [PubMed abstract]
67. Margetts BM, Beilin L, Armstrong BK, Vandongen R. Vegetarian diet in the treatment of mild hypertension: a randomized controlled trial. J Hypertens 1985:S429-31. [PubMed abstract]
68. Beilin LJ, Armstrong BK, Margetts BM, Rouse IL, Vandongen R. Vegetarian diet and blood pressure. Nephron 1987;47:37-41. [PubMed abstract]
69. Berkow SE, Barnard ND. Blood pressure regulation and vegetarian diets. Nutr Rev 2005;63:1-8. [PubMed abstract]
70. Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure. N Engl J Med 1997;336:1117-24. [PubMed abstract]
71. Slattery M, Edwards S, Boucher K, Anderson K, Caan B. Lifestyle and colon cancer: an assessment of factors associated with risk. Am J Epidemiol 1999;150:869-77. [PubMed abstract]
72. Kampman E, Slattery M, Bette C, Potter J. Calcium, vitamin D, sunshine exposure, dairy products, and colon cancer risk. Cancer Causes Control 2000;11:459-66. [PubMed abstract]
73. Holt P, Atillasoy E, Gilman J, Guss J, Moss SF, Newmark H, et al. Modulation of abnormal colonic epithelial cell proliferation and differentiation by low-fat dairy foods. JAMA 1998;280:1074-9. [PubMed abstract]

                Airborne        Tablet

                  Calcium Carbonate 600mg 

                                             +

                             Vitamin D3 400 IU